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European Union

IVDR (In Vitro Diagnostic Regulation)

The EU regulation governing in vitro diagnostic devices — the IVD counterpart to the MDR.

To verifyUpdated May 20, 2026·Issued by EU Notified Body; enforced via national competent authorities
In Vitro DiagnosticsCompanion DiagnosticsSelf-testing IVDs

Overview

What IVDR is and why it matters

Regulation (EU) 2017/746 governs in vitro diagnostic medical devices in the EU/EEA. It introduced a risk-based classification system (Class A–D) and dramatically expanded the share of IVDs requiring Notified Body involvement compared to the prior IVD Directive.

Requirements

What you'll need

  • Risk-based classification (Class A–D)
  • Notified Body involvement for most Class B–D devices
  • Performance evaluation covering analytical and clinical performance
  • Technical documentation
  • Quality management system per ISO 13485
  • EUDAMED registration

Typical timeline

624 months

Class D IVDs (highest risk, e.g. blood-screening tests) face the most Notified Body scrutiny and the longest timelines.

Estimated cost

$20k$200k

Higher-risk classes with clinical performance studies carry substantially higher cost than the equivalent device class under the old IVDD.

Timelines and costs above are typical ranges illustrating general market patterns, not a quote or regulatory conclusion for your specific product. Actual figures depend on device classification, target country, and applicant readiness — professional review is required before relying on this for a business decision.

Where this applies

Applicable countries

all EU/EEA member states

FAQ

Frequently asked questions

Why did my IVD suddenly need a Notified Body?+

IVDR moved roughly 80% of IVDs into categories requiring Notified Body review, versus roughly 20% under the previous IVDD — many previously self-certified products are newly in scope.

Reviewed launch planning

Ready to start your IVDR project?

GHMAP structures your certification path, evidence gaps, and next actions — then connects you with a qualified consultant if you need one.

Professional review remains part of the workflow.